Practical tips

Cannabis and antidepressants - can antidepressants be combined with cannabidiol and marijuana, liver interactions

Drug interactions, Practical tips

Cannabis and antidepressants – can antidepressants be combined with CBD and marijuana?

CBD inhibits CYP2D6, CYP3A4, CYP2C19 and increases the concentration of SSRIs by 25-35% (PMC, 2021). Learn about the mechanisms of interactions, the risk of serotonin syndrome, and psychiatric recommendations.

Michał Waluk
2026-05-04

The side effects of cannabis abuse - who must consider the increased risk of heart failure? - Practical advice

Practical tips, Side effects

Side effects of cannabis abuse – who is at increased risk of heart failure?

Daily smoking of cannabis increases the risk of heart failure by 34% (JAHA, 2024). Patients with coronary artery disease, arrhythmias, and those who have had a myocardial infarction are in the highest risk group.