Researchers Explain CBD's Mechanism of Action in Inflammation
CBD's mechanism of action in inflammation - PPAR gamma, A2A, NF-kB, 15-LOX-1, TNF-alpha, IL-6, IL-17, microbiota, Nrf2. 2023-2026 research accessible.
Michał Waluk
Owner of u Bucha — a CBD cannabis store in Warsaw (Metro Nowy Świat-Uniwersytet). Since [year], I have been selecting CBD products, adaptogens, and supplements that support sleep, recovery, and immunity. I work directly with customers in the physical store, test products, and keep track of the latest clinical research on cannabinoids.
Cannabis for endometriosis – how can it help? Complete guide 2026
Cannabis for Endometriosis - THC, CBD, Medical Marijuana. Pelvic pain affects 10% of women of reproductive age (WHO, 2023). Research, dosing, Polish realities.
CBG + CBD and other hemp cannabinoids – use together or separately?
A complete guide to combining CBG, CBD, CBN, CBC, and THCV. The entourage effect, scientific evidence, dosing protocols, costs, and safety in light of research from 2020-2024.
How do CBD and other hemp cannabinoids affect the human body?
How CBD, CBG, CBN, CBC, and THCV act on CB1 and CB2 receptors, how they are absorbed, metabolized, and excreted. Bioavailability, interactions, and dosing according to evidence-based.
CBD and Sex – How Does Cannabidiol Affect Your Intimate Life? 2026 Guide
CBD and sex: impact on libido, pain, anxiety, and dyspareunia. In the Kasman survey, 68.5% of participants reported improved sexual satisfaction (J Sex Med, 2020).
Combining Cannabis and Tobacco is a Bad Idea – Effects on Lungs, Anxiety and Depression
Combining cannabis with tobacco doubles the risk of depression (Nature, 2024) and brings 70 carcinogens. Discover alternatives: vaporizers, hemp papers, herbal substitutes.
Endocannabinoids and Stress – How Anandamide and 2-AG Work Similar to CBD and THC
Endocannabinoids (anandamide, 2-AG) alleviate stress similarly to CBD and THC. 44% of adult Poles experience chronic stress (CBOS, 2023). Learn about the ECS and the CED hypothesis.
CBD in schizophrenia, research on the antipsychotic effects of cannabis
CBD in schizophrenia, research on the antipsychotic effects of cannabis - Medical and health applications
Cannabis edibles with CBD and THC relieve pain and improve cognitive function in cancer patients
Analysis of the study by Bidwell et al. 2023/2024 (University of Colorado Boulder, n=25) on cannabis edibles with CBD and THC in oncology patients. Comparison with Tramer 2001, Abrams 2020, and Good 2020. Practical protocol for palliative support in Poland with the consent of the oncologist.
Cannabis Treatment for Neuropathic Pain – Clinical Trials, Dosage, and Safety 2026
Treatment of neuropathic pain with cannabis: Hamburg study of 99 patients (NRS 7.5 to 3.75), Cochrane 2018 NNT 20, protocols for CBD and THC, interactions with gabapentin and pregabalin.
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